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Published on: November 8, 2018
Admix'em: a flexible framework for forward-time simulations of hybrid populations with selection and mate choice
Rongfeng Cui1, Molly Schumer2, Gil G Rosenthal3
1Department of Biology, Texas A&M University, College Station, TX 77843, USA, Centro De Investigaciones Científicas De Las Huastecas "Aguazarca", Calnali, Mexico and Max Planck Institute for the Biology of Aging, Cologne, Germany.
Unlabelled:
We introduce a new forward-time simulator, Admix'em, that allows for rapid and realistic simulations of admixed populations with selection. Complex selection can be achieved through user-defined fitness and mating-preference probability functions. Users can specify realistic genomic landscapes and model neutral SNPs in addition to sites under selection. Admix'em is designed to simulate selection in admixed populations but can also be used as a general population simulator. Usage and examples are in the supplement.
Availability And Implementation:
C ++ and OpenMP, supports 64-bit Linux/Unix-like platforms. https://github.com/melop/admixem
Contact:
rcui@age.mpg.de
Supplementary Information:
Supplementary data are available at Bioinformatics online.
Related Concept Videos
Mate Choice
Hardy-Weinberg Principle
Hybrid Zones
Types of Selection
Mutation, Gene Flow, and Genetic Drift
Inclusive Fitness

