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Updated: Mar 29, 2026

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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TAS-102: a novel antimetabolite for the 21st century

Nataliya Uboha1, Howard S Hochster2

  • 1University of Wisconsin, Madison, WI 53706, USA.

Future Oncology (London, England)
|December 1, 2015
PubMed

Keywords:
TAS-102antiangiogenesiscolorectal cancerfluoropyrimidine resistancefluoropyrimidinestrifluorothymidine

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