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Recurrence rate of lentigo maligna after micrographically controlled staged surgical excision
K de Vries1,2, K Greveling2, L M Prens2
1Department of Dermatology, University Medical Center Groningen, Groningen, the Netherlands.
The British Journal of Dermatology
|December 1, 2015
Summary
Staged surgical excision shows lower recurrence rates for lentigo maligna compared to standard wide local excision. This method offers superior clearance and should be prioritized in treatment guidelines.
Area of Science:
- Dermatology
- Surgical Oncology
Background:
- Lentigo maligna is a slow-growing melanoma in situ.
- Current guidelines recommend wide local excision (5 mm margin) with 6-20% recurrence rates.
Purpose of the Study:
- To evaluate the recurrence rate of lentigo maligna after staged surgical excision.
Main Methods:
- Retrospective analysis of 100 patients treated with staged surgical excision (2002-2011).
- Utilized Sympathy program linked to PALGA for recurrence identification.
- 100% immunohistopathological control of lateral margins with digital imaging support.
Main Results:
- Mean follow-up of 60 months for 100 patients.
- Four recurrences observed at 37, 58, 74, and 77 months.
- Staged surgical excision achieved high clearance rates.
Conclusions:
- Staged surgical excision demonstrates superior clearance and lower recurrence rates than wide local excision for lentigo maligna.
- This technique should be considered a primary treatment option in guidelines.
