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Flg22-Triggered Immunity Negatively Regulates Key BR Biosynthetic Genes
Tamara Jiménez-Góngora1, Seong-Ki Kim2, Rosa Lozano-Durán1
1The Sainsbury Laboratory , Norwich, UK ; Shanghai Center for Plant Stress Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences , Shanghai, China.
Plant growth and immunity involve a trade-off. Brassinosteroids (BR) promote growth but suppress immunity. New findings reveal pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) reduces BR biosynthesis, suggesting bidirectional crosstalk.
Area of Science:
- Plant biology
- Molecular plant pathology
- Hormone signaling
Background:
- Plant growth and immunity are opposing processes, involving a trade-off.
- Brassinosteroids (BR) are growth-promoting hormones that negatively regulate pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI).
- Previous research suggested a unidirectional negative crosstalk from PTI to BR signaling.
Purpose of the Study:
- To investigate the bidirectional crosstalk between BR and PTI signaling pathways.
- To determine if PTI activation affects BR biosynthesis.
Main Methods:
- Treatment of plants with the bacterial PAMP flg22.
- Analysis of brassinosteroid (BR) biosynthetic gene expression.
- Assessment of BR perception and signaling pathways.
Main Results:
- Activation of PTI by flg22 rapidly reduces the expression of BR biosynthetic genes.
- This repression of gene expression occurs within 15 minutes of flg22 treatment.
- The PTI-induced effect on BR biosynthesis does not require BR perception or signaling.
Conclusions:
- The crosstalk between PTI and BR signaling is bidirectional, not unidirectional.
- PTI activation can lead to reduced BR biosynthesis, impacting plant growth and defense.
- This bidirectional interaction is crucial for understanding plant responses to pathogens.
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