Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

1.4K
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
1.4K
Cerebellum: Anatomical Regions01:17

Cerebellum: Anatomical Regions

5.6K
The cerebellum, also known as the "little brain," is located in the posterior cranial fossa, inferior to the tentorium cerebelli and dorsal to the brainstem. It plays a significant role in motor control, coordination, and proprioception.
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...
5.6K
Higher Mental Functions of Brain: Learning and Memory01:26

Higher Mental Functions of Brain: Learning and Memory

2.3K
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
2.3K
Associative Learning01:27

Associative Learning

1.9K
Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
1.9K
Diencephalon: Thalamus and Information Relay01:27

Diencephalon: Thalamus and Information Relay

5.5K
The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is  a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological...
5.5K
Cognitive Learning01:21

Cognitive Learning

1.5K
Cognitive learning is based on purposive behavior, incidental learning, and insight learning.
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Use of extended reality head-mounted displays in US health care education: a scoping review.

Frontiers in medicine·2026
Same author

Hippocampal conditioning code dominates and disrupts the place code.

bioRxiv : the preprint server for biology·2026
Same author

Revealing gait as a murine biomarker of injury, disease, and age with multivariate statistics and machine learning.

Scientific reports·2025
Same author

Short-Chain Fatty Acid Supplementation After Traumatic Brain Injury Attenuates Neurologic Injury Via the Gut-Brain-Microglia Axis.

Shock (Augusta, Ga.)·2025
Same author

Closed-loop control of theta oscillations enhances human hippocampal network connectivity.

Nature communications·2025
Same author

Ketamine does not rescue plaque load or gap detection in the 5XFAD mouse model of Alzheimer's disease.

Frontiers in aging neuroscience·2025
Same journal

The epigenetics of memory storage in the brain.

Cellscience·2021
Same journal

Influenza antigenic drift: what is the driving force?

Cellscience·2021
Same journal

The emerging role of CCN6 in breast cancer invasion.

Cellscience·2017
Same journal

The role of CCK8 in the inhibition of glucose production.

Cellscience·2017
Same journal

How can studying psychopaths help us understand the neural mechanisms of moral judgment?

Cellscience·2015
Same journal

Novel insights into non-image forming visual processing in the retina.

Cellscience·2011
See all related articles

Related Experiment Video

Updated: Mar 29, 2026

A Flexible Platform for Monitoring Cerebellum-Dependent Sensory Associative Learning
11:32

A Flexible Platform for Monitoring Cerebellum-Dependent Sensory Associative Learning

Published on: January 19, 2022

4.0K

Forebrain-Cerebellar Interactions During Learning.

Craig Weiss1, Aldis P Weible1, Roberto Galvez1

  • 1Department of Physiology, Interdepartmental Neuroscience Program, Northwestern University Feinberg School of Medicine, 303 East Chicago Ave., Chicago, IL 60611-3008.

Cellscience
|December 1, 2015
PubMed
Summary
This summary is machine-generated.

The brain

More Related Videos

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum
11:47

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum

Published on: February 15, 2015

30.4K
A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging
11:50

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

Published on: February 4, 2022

4.7K

Related Experiment Videos

Last Updated: Mar 29, 2026

A Flexible Platform for Monitoring Cerebellum-Dependent Sensory Associative Learning
11:32

A Flexible Platform for Monitoring Cerebellum-Dependent Sensory Associative Learning

Published on: January 19, 2022

4.0K
Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum
11:47

Modulating Cognition Using Transcranial Direct Current Stimulation of the Cerebellum

Published on: February 15, 2015

30.4K
A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging
11:50

A Standardized Pipeline for Examining Human Cerebellar Grey Matter Morphometry using Structural Magnetic Resonance Imaging

Published on: February 4, 2022

4.7K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Motor Control

Background:

  • The cerebral cortex and cerebellum are crucial for coordinated, goal-directed movements.
  • Understanding cerebro-cerebellar interactions is key to explaining conditioned responses.
  • Trace eyeblink conditioning provides a model for studying these interactions.

Purpose of the Study:

  • To review progress in understanding neural substrates of cerebro-cerebellar interactions during learning.
  • To detail the roles of the hippocampus and prefrontal cortex in trace eyeblink conditioning.
  • To elucidate the circuitry facilitating pontine input to the cerebellum for conditioned responses.

Main Methods:

  • Review of existing literature on trace eyeblink conditioning.
  • Analysis of forebrain-dependent learning paradigms.
  • Examination of neural circuitry, including the hippocampus, prefrontal cortex, and cerebellum.

Main Results:

  • The hippocampus and prefrontal cortex are vital for acquiring conditioned responses.
  • Specific circuitry facilitates pontine input to the cerebellum, essential for conditioning.
  • Permanent changes in sensory cortex, basal ganglia, and prefrontal cortex homologues bridge the trace interval.

Conclusions:

  • Cerebro-cerebellar interactions are fundamental for learning and consolidating conditioned responses.
  • The hippocampus, prefrontal cortex, and sensory cortex play critical roles in trace eyeblink conditioning.
  • These neural systems collectively enable the cerebellum to produce well-timed conditioned responses.