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Updated: Mar 29, 2026

A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
Undiagnosed Hepatocellular Carcinoma Presenting as Nasal Metastases
Hassen Mohammed1, Rashid Sheikh1, Waheed Rahman1
1Department of Otorhinolaryngology and Head & Neck Surgery, Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar.
Abstract:
Hepatocellular carcinoma (HCC) is a primary malignancy of the liver with up to half of cases suffering from extrahepatic metastasis in the later stages of the disease. Commonly reported and encountered metastatic sites include the lymph nodes, lung, bone, and adrenal glands. This is an effort to throw a spotlight on a rare case of metastatic HCC which presented to us as two distinct lesions in the nose. It focuses on the presentation and the steps that were taken to reach this rare and unusual diagnosis. It sparks interest from a clinical and histopathology perspective. Our cynosure is the findings of the case coupled with a probe on the possible routes of spread of HCC to sinonasal region.
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