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Published on: February 17, 2023
A Case of Cronobacter (Enterobacter sakazakii) Bacteremia in a Breastfed Infant
1Florida State University Pediatric Residency Program at Sacred Heart Hospital, Pensacola tangrabroge@yahoo.com.
Insights
Cronobacter can cause infant infections, often linked to powdered infant formula. This case highlights a rare instance of Cronobacter bacteremia in a breastfed infant, suggesting broader exposure risks.
Area of Science:
- Microbiology and Infectious Diseases
- Public Health and Epidemiology
- Pediatric Medicine
Background:
- Cronobacter, a genus within Enterobacteriaceae, was identified in 2007.
- Contaminated powdered infant formula (PIF) is a known source of invasive Cronobacter infections in infants.
- Expert panels from the FAO and WHO confirmed PIF contamination as a cause of infant illness.
Purpose of the Study:
- To report a rare case of Cronobacter bacteremia in an exclusively breastfed infant.
- To underscore potential exposure routes for Cronobacter beyond PIF.
- To contribute to the understanding of Cronobacter epidemiology in vulnerable populations.
Main Methods:
- Case report detailing a clinical presentation.
- Review of relevant literature on Cronobacter infections and exposure sources.
- Microbiological identification and characterization (implied).
Main Results:
- A case of Cronobacter bacteremia was identified in an exclusively breastfed infant.
- The infant's mother was a healthcare worker, suggesting potential occupational exposure.
- This represents an unusual transmission pathway for Cronobacter.
Conclusions:
- Cronobacter infections in infants can occur through routes other than contaminated PIF.
- Breastfeeding does not inherently prevent Cronobacter exposure if the source is environmental or occupational.
- Further investigation into non-PIF sources of Cronobacter exposure is warranted.
Abstract:
Cronobacter multispecies complex (Cronobacter) is a member of the Enterobacteriaceae family that was described as a new genus in 2007 [ 1]. Consumption of contaminated powdered infant formula (PIF) has been associated with invasive Cronobacter infection in infants [ 1, 2]. The Food and Agricultural Organization and World Health Organization expert consultations in 2004 and 2006 concluded that Cronobacter contamination of PIF did cause infection and disease in infants [ 2]. Although the presence of Cronobacter in PIF is well documented, the nature of this organism may lead to exposure through other sources [ 1, 3]. Our case illustrates a rare example of Cronobacter bacteremia in an exclusively breastfed infant of a healthcare worker.
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