Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

2.1K
Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
2.1K
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies01:28

Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies

782
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
782
Peptic Ulcer01:27

Peptic Ulcer

30
Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the...
30
Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

1.1K
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
1.1K
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

635
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
635
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

1.7K
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical, Dietary, Lifestyle and Genetic Factors Associated With Age at Onset of Esophageal Adenocarcinoma.

United European gastroenterology journal·2026
Same author

Liver Transplantation After Immune Checkpoint Inhibition in Hepatocellular Carcinoma-Data From the Multinational LITCHI Registry.

Liver international : official journal of the International Association for the Study of the Liver·2026
Same author

Multicenter study of bleeding and thromboembolic events with durvalumab tremelimumab vs. atezolizumab and bevacizumab in advanced HCC.

JHEP reports : innovation in hepatology·2026
Same author

Rituximab limits glucocorticoid use in IgG4-related disease: Real-world evidence from a large European cohort.

European journal of internal medicine·2026
Same author

Novel insights into autoimmune gastritis: clinical profile and gastric neoplastic risk from an international multicentre study.

Gut·2026
Same author

What Is New in the German S3 Guideline on Gastric Cancer: Diagnosis, Staging, and Treatment.

Oncology research and treatment·2026

Related Experiment Video

Updated: Mar 29, 2026

Author Spotlight: Detection and Treatment of Helicobacter pylori Infection
06:40

Author Spotlight: Detection and Treatment of Helicobacter pylori Infection

Published on: July 28, 2023

4.7K

Helicobacter pylori screening: options and challenges.

Marino Venerito1, Elisabetta Goni1, Peter Malfertheiner1

  • 1a Department of Gastroenterology, Hepatology and Infectious Diseases , Otto-von-Guericke University Hospital , Magdeburg , Germany.

Expert Review of Gastroenterology & Hepatology
|December 2, 2015
PubMed
Summary
This summary is machine-generated.

Helicobacter pylori (H. pylori) infection causes gastritis and increases risks for peptic ulcers and gastric cancer. Early detection and treatment, especially in high-risk groups, are key for prevention.

Keywords:
Helicobacter pylorigastric cancernon-steroidal anti-inflammatory drugspeptic ulcer diseasepreventionscreeningvaccine

More Related Videos

Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
03:33

Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology

Published on: May 23, 2025

1.1K
Detection of Helicobacter pylori Infection and Antibiotic Resistance via Stool Quantitative Polymerase Chain Reaction Analysis
04:56

Detection of Helicobacter pylori Infection and Antibiotic Resistance via Stool Quantitative Polymerase Chain Reaction Analysis

Published on: May 16, 2025

1.4K

Related Experiment Videos

Last Updated: Mar 29, 2026

Author Spotlight: Detection and Treatment of Helicobacter pylori Infection
06:40

Author Spotlight: Detection and Treatment of Helicobacter pylori Infection

Published on: July 28, 2023

4.7K
Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
03:33

Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology

Published on: May 23, 2025

1.1K
Detection of Helicobacter pylori Infection and Antibiotic Resistance via Stool Quantitative Polymerase Chain Reaction Analysis
04:56

Detection of Helicobacter pylori Infection and Antibiotic Resistance via Stool Quantitative Polymerase Chain Reaction Analysis

Published on: May 16, 2025

1.4K

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Oncology

Background:

  • Helicobacter pylori gastritis is the most common gastrointestinal infection.
  • This infection can lead to severe conditions like peptic ulcer disease, gastric cancer (GC), and MALT-lymphoma in up to 20% of cases.

Purpose of the Study:

  • To review the clinical implications of H. pylori infection.
  • To discuss H. pylori screen-and-treat strategies for gastric cancer prevention.
  • To explore prevention strategies for H. pylori-related complications, particularly in patients using NSAIDs and aspirin.

Main Methods:

  • Literature review of H. pylori infection, its sequelae, and prevention strategies.
  • Analysis of the efficacy of H. pylori screen-and-treat approaches.
  • Evaluation of vaccination as a potential eradication method.

Main Results:

  • The H. pylori screen-and-treat strategy is most effective for primary gastric cancer prevention in individuals without precancerous conditions, particularly in high-incidence communities and relatives of GC patients.
  • Special consideration is needed for patients on non-steroidal anti-inflammatory drugs (NSAIDs) and low-dose aspirin.
  • A novel H. pylori vaccine shows promise but requires further study on long-term effects.

Conclusions:

  • H. pylori management is crucial for preventing serious gastrointestinal diseases.
  • Targeted screening and treatment strategies are vital, especially in high-risk populations.
  • Vaccination offers a potential future avenue for H. pylori eradication, pending long-term safety data.