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Updated: Mar 29, 2026

Fabrication of Tongue Extracellular Matrix and Reconstitution of Tongue Squamous Cell Carcinoma In Vitro
Published on: June 20, 2018
Carcinoma Tongue--Clinicopathological Presentation
K R Majumder1, R Karmakar, M M Alam
1Dr Krisna Rani Majumder, Assistant Professor, Department of Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.
Abstract:
This prospective study was done to observe the diversity of clinical presentation of carcinoma of tongue and to study the pathological variety of carcinoma of tongue and was conducted in the Department of General Surgery and Otolaryngology and Head Neck Surgery in Bangabandhu Sheikh Mujib Medical University, Dhaka Medical College Hospital on 50 patients from January 2011 to July 2013. In this series highest number of patients were middle aged (36%). Male female ratio was 2:1. Average socioeconomic conditions of the patient were poor (68%). Betel nut and leaves chewing (88%) and smoking (56%) habits were commonly practiced for more than 10 years among the patients. Depending on site of involvement, variation in presenting symptoms has been observed. Oral tongue carcinoma mostly was presented with tongue lesion, pain and dysphagia where as the carcinoma of base of tongue commonly was presented with dysphagia, lump in neck. Lateral border of tongue (60%) was seen commonly involved. Ulcerative lesion (56%) predominantly was found in tongue lesion. Eighty percent (80%) of cases had no palpable Lymph node. Only few patients were found with Lymph node metastasis and most of them had carcinoma in base of the tongue (75%). Most of the carcinoma was well differentiated Squamous cell carcinoma. Carcinoma of tongue in our study commonly found in middle aged male patients. Variation of symptoms has depended on anatomical site involved. Most of the carcinoma was well differentiated Squamous cell carcinoma. Carcinoma other than squamous cell was not found.
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