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Repressible Operon: trp Operon01:21

Repressible Operon: trp Operon

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The trp operon in Escherichia coli exemplifies a repressible operon. It regulates the synthesis of tryptophan through repressor-mediated transcriptional control and attenuation. This dual regulatory mechanism ensures tryptophan biosynthesis occurs only when needed, conserving cellular resources.Structure of the trp OperonThe trp operon consists of five structural genes (trpE, trpD, trpC, trpB, and trpA) that encode enzymes for tryptophan biosynthesis. These genes are transcribed as a single...
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Magnetic bacteria exhibit a directed movement called magnetotaxis, driven by structures called magnetosomes. These magnetosomes consist of chains of magnetic particles made of either magnetite (Fe₃O₄) or greigite (Fe₃S₄) and are organized in a linear conformation by a protein scaffold within invaginations of the cell membrane. The bacteria align along the north–south magnetic field lines, much like a compass needle. They are typically microaerophilic or anaerobic...
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Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
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Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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Updated: Mar 29, 2026

Inducible and Reversible Dominant-negative DN Protein Inhibition
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Deciphering durable resistance one R gene at a time.

Frank F White1, Wolf Frommer2

  • 1Department of Plant Pathology, University of Florida, Gainesville, Florida, USA.

Nature Genetics
|December 2, 2015
PubMed
Summary

Wheat gene Lr67 characterization reveals sugar transport

Area of Science:

  • Plant genetics
  • Molecular biology
  • Crop science

Background:

  • Durable resistance genes are crucial for crop protection.
  • Understanding plant-pathogen interactions is key to developing resistant crops.

Purpose of the Study:

  • To characterize the wheat gene Lr67 and its role in disease resistance.
  • To investigate the link between sugar transport and fungal pathogen colonization in wheat.

Main Methods:

  • Gene expression analysis
  • Pathogen infection assays
  • Sugar transport assays

Main Results:

  • The wheat gene Lr67 influences sugar transport within the plant.
  • Altered sugar transport affects the susceptibility of wheat to a broad range of fungal pathogens.

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  • Lr67 plays a significant role in broad-spectrum disease resistance.

    • Conclusions:

    • Management of sugar transport is a critical factor in plant defense against fungal pathogens.
    • The wheat gene Lr67 offers a potential target for engineering durable disease resistance in crops.