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Updated: Mar 29, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Saggy skin as a presenting sign of angioimmunoblastic T-cell lymphoma
N G Maher1,2, Y Z Chiang1, X Badoux2,3
1Department of Dermatology, St George Hospital, Kogarah, Sydney, NSW, Australia.
Abstract:
Angioimmunoblastic T-cell lymphoma (AITL) is a rare, aggressive form of peripheral T-cell lymphoma that has a variety of cutaneous manifestations. To our knowledge, saggy skin has not been documented as one of these manifestations. We report a case of a patient with angioimmunoblastic T-cell lymphoma presenting initially with pruritus and saggy skin, which later progressed into erythroderma despite chemotherapy; the disease eventually resolved with autologous stem cell transplant. Appreciating the cutaneous manifestations of AITL may allow for earlier diagnosis and treatment.
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