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Intracerebroventricular administration of insulin attenuates retrieval of a passive avoidance response in rats
H Schwarzberg1, H G Bernstein, M Reiser
1Institute of Physiology, Medical Academy Magdeburg, German Democratic Republic.
Neuropeptides
|February 1, 1989
Abstract:
The effect of intracerebroventricularly applied insulin on one-trial learning passive avoidance behaviour has been studied in rats. Treatment with 10.3 pmole insulin 1 hr before the 24 hr retention test attenuated passive avoidance behaviour at both the 24 hr and 48 hr retention trials. The data suggest that insulin may play a role in processes relating to the retrieval of information stored in the brain.