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Updated: Mar 29, 2026
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Irreversible Electroporation
1Division of Vascular and Interventional Radiology, Department of Radiology, University of Miami-Miller School of Medicine, Miami, Florida.
Abstract:
Irreversible electroporation (IRE) is a predominantly nonthermal ablative technology that uses high-voltage, low-energy DC current pulses to induce cell death. Thermal ablative technologies such as radiofrequency ablation, microwave ablation, and cryoablation have several applications in oncology but have limitations that have been established. IRE has shown promise to overcome some of these limitations. This article reviews the basics of the technology, patient selection, clinical applications, practical pointers, and the published data.
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