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Related Experiment Videos

Simon nitinol inferior vena cava filter: initial clinical experience. Work in progress.

M Simon1, C A Athanasoulis, D Kim

  • 1Department of Radiology, Beth Israel Hospital, Harvard Medical School, Boston, MA 02115.

Radiology
|July 1, 1989
PubMed
Summary

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The Simon nitinol filter effectively prevents pulmonary embolism by interrupting the vena cava. This multicenter trial shows safe insertion and no migration, with manageable occlusion rates.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiology

Background:

  • Pulmonary embolism (PE) is a significant cause of morbidity and mortality.
  • Inferior Vena Cava (IVC) filters are used to prevent PE in high-risk patients.
  • The Simon nitinol filter is a novel device for IVC interruption.

Purpose of the Study:

  • To report preliminary clinical results of the Simon nitinol filter in a multicenter clinical trial.
  • To assess the safety and efficacy of the filter for preventing pulmonary embolism.
  • To analyze filter placement, complications, and outcomes.

Main Methods:

  • A multicenter clinical trial involving 103 patients across 17 US centers.
  • Filter insertion via femoral or jugular routes using a 9-F catheter.

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  • Follow-up included radiography, ultrasonography, MR imaging, and clinical evaluation.

    • Main Results:

    • Successful filter insertion in all patients with no significant procedural complications.
    • No instances of filter migration or perforation observed in 103 patients.
    • Symptomatic occlusion rates of 7%-9%, with asymptomatic occlusions detected by MR imaging.

    Conclusions:

    • The Simon nitinol filter demonstrates a safe and effective method for IVC interruption.
    • The device shows promising results in preventing pulmonary embolism.
    • Further investigation into the implications of filter occlusion is warranted.