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Digital PCR for Quantifying Circulating MicroRNAs in Acute Myocardial Infarction and Cardiovascular Disease
Published on: July 3, 2018
Diagnostic markers of acute myocardial infarction
Sabesan Mythili1, Narasimhan Malathi1
1Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Chennai, Tamil Nadu 600116, India.
Insights
Early diagnosis of acute myocardial infarction (AMI) is crucial for patient survival. This review details cardiac biomarkers essential for identifying cardiac ischemia and improving AMI patient outcomes.
Area of Science:
- Cardiology
- Biochemistry
Background:
- Acute myocardial infarction (AMI) is a leading global cause of death.
- Prompt diagnosis of cardiac ischemia is vital for effective AMI management.
- Misdiagnosis of chest pain can lead to incorrect hospital admissions.
Purpose of the Study:
- To review the various cardiac biomarkers released during acute myocardial infarction (AMI).
- To highlight the importance of cardiac biomarkers in the early diagnosis of cardiac ischemia.
Main Methods:
- Literature review of studies on cardiac biomarkers in AMI.
- Analysis of diagnostic roles of clinical history, physical examination, ECG, and biomarkers.
Main Results:
- Cardiac biomarkers are critical in differentiating cardiac ischemia from other causes of chest pain.
- Accurate assessment of biomarkers aids in timely and appropriate patient management.
Conclusions:
- Cardiac biomarkers play a pivotal role in the early and accurate diagnosis of AMI.
- Effective utilization of biomarkers can significantly improve patient outcomes in AMI.
Abstract:
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. The highest risk of fatality occurs within the initial hours of onset of AMI. Thus, early diagnosis of cardiac ischemia is critical for the effective management of patients with AMI. Improper diagnosis of patients with chest pain often leads to inappropriate admission of patients without AMI and vice versa. In addition to clinical history, physical examination, accurate electrocardiogram findings and assessment of cardiac biomarkers have an important role in the early diagnosis of acute ischemia. The present review discusses in detail the various cardiac biomarkers released during the event of an AMI.
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