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Self-assembly of Complex Two-dimensional Shapes from Single-stranded DNA Tiles
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Sequence-dependent structural changes in a self-assembling DNA oligonucleotide

Maithili Saoji1, Paul J Paukstelis1

  • 1Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.

Acta Crystallographica. Section D, Biological Crystallography
|December 3, 2015
PubMed
Summary

A single nucleotide addition dramatically alters DNA nanostructure formation. This study reveals how sequence dictates DNA folding through altered noncanonical base pairing, impacting crystallization outcomes.

Keywords:
DNA structurebase-triple interactionsself-assemblysequence–structure relationshipsheared G–A base pair

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