Related Experiment Video
Updated: Mar 29, 2026

Kidney Procurement in a Preclinical Large Animal Model
Published on: May 2, 2025
Live kidney donation from a person with haemophilia
Christopher McCauley1, Agnes Masengu2, Aisling E Courtney2
1Department of Haematology, Belfast City Hospital, Belfast, UK.
Abstract:
There are many documented cases of a person with haemophilia successfully receiving a solid organ transplant, including liver and kidney. However, there is no literature reporting live organ donation by a person with haemophilia. Presumably, this is because the associated risks of excessive bleeding, inhibitor development after a period of intensive treatment with factor replacement and the possibility of variant Creutzfeldt-Jakob disease transmission in those previously treated with blood products, are considered excessive. This case describes a 24-year-old man who was diagnosed with mild haemophilia A during his pretransplant work up as a potential live kidney donor to his sister. He then went on to successfully donate his kidney, without complications. To the best of our knowledge, this is the first description of a person with haemophilia being a living organ donor.
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