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Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets
Published on: May 11, 2015
A multidisciplinary guided practical on type I diabetes engaging students in inquiry-based learning.
M Mingueneau1, A Chaix2, N Scotti3
1Centre d'Immunologie de Marseille Luminy, Aix-Marseille Université-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique, Parc Scientifique en Technologique de Luminy, Marseille, France; michael_mingueneau@biogen.com.
This workshop improved high school students' understanding of diabetes research and scientific reasoning. Students learned about glycemia regulation and therapeutic strategies through hands-on experiments.
Area of Science:
- Biomedical Sciences
- Endocrinology
- Science Education
Background:
- Type I diabetes management requires understanding glycemia regulation.
- Fundamental research is crucial for developing new therapeutic strategies.
- Engaging students in scientific inquiry enhances learning.
Purpose of the Study:
- To describe a 3-day workshop on type I diabetes for high school students.
- To illustrate how glycemia regulation research informs scientific knowledge and therapies.
- To assess the workshop's impact on student understanding of the scientific process.
Main Methods:
- Interactive workshop format with guided and open-ended investigations.
- Small group work with doctoral and postdoctoral mentors.
- Student-led questioning, hypothesis generation, and experimental design.
- Pre- and post-workshop questionnaires and poster presentations for evaluation.
Main Results:
- Students recognized the need for animal models in diabetes research.
- Workshop successfully enhanced student awareness of scientific reasoning.
- Improved understanding of the research process and therapeutic development.
Conclusions:
- Hands-on educational approaches effectively improve scientific literacy.
- Inquiry-based learning fosters critical thinking in young students.
- Connecting fundamental research to clinical applications motivates scientific exploration.
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Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type I Diabetes I: Introduction
Type I Diabetes II: Pathophysiology
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Type II Diabetes I: Introduction
Type II Diabetes II: Pathophysiology

