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Updated: Mar 29, 2026

Development of a Human Preclinical Model of Osteoclastogenesis from Peripheral Blood Monocytes Co-cultured with Breast Cancer Cell Lines
Published on: September 13, 2017
Aggressive Metaplastic Carcinoma of the Breast with Osteoclastic Giant Cells
Kathleen Khong1, Yanhong Zhang2, Mary Tomic2
1Department of Radiology, University of California, Davis Medical Center, Sacramento, USA.
Abstract:
Metaplastic carcinoma of the breast is an uncommon type of malignancy that is aggressive but can mimic other benign breast neoplastic processes on imaging. We present a case of a young female patient who presented with a rapidly progressing metaplastic carcinoma with osteoclastic giant cells subtype. There have been only very rare published reports of this pathologic subtype of metaplastic carcinoma containing osteoclastic giant cells.
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