Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dementia. A review emphasizing clinicopathologic correlation and brain-behavior relationships.

H C Chui1

  • 1Department of Neurology, University of Southern California School of Medicine, Los Angeles.

Archives of Neurology
|July 1, 1989
PubMed
Summary

This review explores dementia, a progressive cognitive decline, and its link to brain function. Understanding these brain-behavior relationships is key to diagnosing and treating various dementia types.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Baseline Findings of PreventE4: A Double-Blind Placebo Controlled Clinical Trial Testing High Dose DHA in APOE4 Carriers before the Onset of Dementia.

The journal of prevention of Alzheimer's disease·2023
Same author

Review: Vascular dementia: clinicopathologic and genetic considerations.

Neuropathology and applied neurobiology·2018
Same author

Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models.

Translational psychiatry·2017
Same author

Beyond-limit light focusing in the intermediate zone.

Optics letters·2011
Same author

MRI shows more severe hippocampal atrophy and shape deformation in hippocampal sclerosis than in Alzheimer's disease.

International journal of Alzheimer's disease·2011
Same author

An inverse association of cardiovascular risk and frontal lobe glucose metabolism.

Neurology·2009

Area of Science:

  • Neurology
  • Neuroscience
  • Cognitive Science

Background:

  • Dementia is characterized by progressive memory and intellectual function loss.
  • Current clinicopathologic classifications of dementia introduce diagnostic uncertainty.
  • Brain substrate is intimately linked to behavior, a concept explored through cortical vs. subcortical dementia classification.

Purpose of the Study:

  • To review brain-behavior relationships in dementia.
  • To examine four specific clinicopathologic entities: Alzheimer's disease, Pick's disease, vascular dementia, and Parkinson's disease.

Main Methods:

  • Review of existing literature on dementia and brain-behavior relationships.
  • Analysis of characteristic behavioral patterns and anatomic pathology associated with specific dementia types.

Related Experiment Videos

Main Results:

  • Dementing illnesses have significantly advanced the understanding of brain-behavior relationships.
  • Specific clinicopathologic entities are associated with distinct behavioral patterns and pathologies.
  • Classification as cortical vs. subcortical dementia provides a simplified model of brain-behavior links.

Conclusions:

  • Resolving diagnostic issues and identifying biological markers are crucial for future progress in dementia research.
  • Further understanding of brain-behavior relationships will aid in managing dementia.