First Aid Oxygen Treatment for Decompression Illness in the Goat After Simulated Submarine Escape

Personnel responding to a distressed submarine incident require information on likely casualty levels and the severity and progression of decompression illness (DCI). Recompression may not be immediately available. First aid oxygen (FAo₂) can be administered; however, there is no direct evidence of its efficacy in this scenario.

Trials were conducted between 2004 and 2006. Goats exposed to raised pressure for 24 h ('saturation') were either returned directly to atmospheric pressure (Phase A, N = 40) or exposed to simulated submarine escape at a depth of 656 ft (200 m; assumed seawater density = 1019.72 kg · m(-3); Phase B, N = 39). The pressure during saturation was selected to provoke 50% DCI. Cases of DCI were randomly assigned to receive FAo₂or air.

DCI cases were: limb pain in 39 subjects, neurological in 6, respiratory in 4, and pulmonary barotrauma in 1 subject. In Phase A, 5/12 subjects in the FAo₂group and 0/11 in the air control group achieved permanent resolution of DCI. In Phase B, 6/8 subjects in the FAo₂group and 5/8 in the air control group achieved permanent resolution. In both Phases, levels of venous gas bubbles reduced sooner with FAo₂. Of three cases of neurological DCI receiving FAo₂, two showed permanent resolution. In total, four cases of respiratory DCI occurred; none of these resolved, with three being treated with FAo₂and one in the air control.

Oxygen can be an effective first aid measure for DCI following submarine escape. However, it should not be used as a replacement for recompression therapy.