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Updated: Mar 29, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
[Postoperative persistent chronic pain: what do we know about prevention, risk factors, and treatment]
Durval Campos Kraychete1, Rioko Kimiko Sakata2, Leticia de Oliveira Carvalho Lannes3
1Departamento de Anestesiologia e Cirurgia, Universidade Federal da Bahia (UFBA), Salvador, BA, Brasil; Sociedade Brasileira para o Estudo da Dor, São Paulo, SP, Brasil; Ambulatório de Dor, Complexo Universitário Prof. Edgar Santos, Salvador, BA, Brasil.
Background And Objectives:
Postoperative persistent chronic pain (POCP) is a serious health problem, disabling, undermining the quality of life of affected patients. Although more studies and research have addressed the possible mechanisms of the evolution from acute pain to chronic postoperatively, there are still no consistent data about the risk factors and prevention. This article aims to bring what is in the panorama of the current literature available.
Content:
This review describes the definition, risk factors, and mechanisms of POCD, its prevention and treatment. The main drugs and techniques are exposed comprehensively.
Conclusion:
Postoperative persistent chronic pain is a complex and still unclear etiology entity, which interferes heavily in the life of the subject. Neuropathic pain resulting from surgical trauma is still the most common expression of this entity. Techniques to prevent nerve injury are recommended and should be used whenever possible. Despite efforts to understand and select risk patients, the management and prevention of this syndrome remain challenging and inappropriate.
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