The Impact of Hepatitis C on Short-Term Outcomes of Total Joint Arthroplasty

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Kimona Issa1, Matthew R Boylan2, Qais Naziri2

  • 1Department of Orthopaedic Surgery, Seton Hall University School of Medicine and Health Sciences, 400 South Orange Avenue, South Orange, NJ 07079.

The Journal of Bone and Joint Surgery. American Volume
|December 4, 2015
PubMed

Insights

Patients with hepatitis C infection face increased risks for complications and longer hospital stays after total joint arthroplasty. Surgeons should discuss these risks, including surgical complications, with patients before procedures.

Area of Science:

  • Orthopaedic Surgery
  • Hepatology
  • Public Health

Background:

  • Advances in hepatitis C treatment improve patient lifespan and quality of life.
  • Growing need for total joint arthroplasty in hepatitis C patients.
  • Limited data on perioperative outcomes for this patient group.

Purpose of the Study:

  • Assess the association between hepatitis C infection and perioperative outcomes.
  • Evaluate risks of lower-extremity total joint arthroplasty in hepatitis C patients.

Main Methods:

  • Analysis of the Nationwide Inpatient Sample database (1998-2010).
  • Matched case-control study comparing hepatitis C patients with controls (3:1 ratio).
  • Outcomes assessed: perioperative complications (medical, surgical) and length of stay.

Main Results:

  • Hepatitis C infection rate increased significantly from 1998 to 2010.
  • Hepatitis C patients had a 30% higher risk of any complication.
  • Increased risk of surgical complications (78%) and longer hospital stays (14%) observed.

Conclusions:

  • Hepatitis C is an increasingly recognized comorbidity in total joint arthroplasty.
  • Patients with hepatitis C face elevated perioperative risks.
  • Shared decision-making is crucial to inform patients of these risks.
Abstract

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