Related Experiment Video
Updated: Mar 29, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Experimental observation of acoustic emissions generated by a pulsed proton beam from a hospital-based clinical
Kevin C Jones1, François Vander Stappen2, Christopher R Bawiec3
1Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Purpose:
To measure the acoustic signal generated by a pulsed proton spill from a hospital-based clinical cyclotron.
Methods:
An electronic function generator modulated the IBA C230 isochronous cyclotron to create a pulsed proton beam. The acoustic emissions generated by the proton beam were measured in water using a hydrophone. The acoustic measurements were repeated with increasing proton current and increasing distance between detector and beam.
Results:
The cyclotron generated proton spills with rise times of 18 μs and a maximum measured instantaneous proton current of 790 nA. Acoustic emissions generated by the proton energy deposition were measured to be on the order of mPa. The origin of the acoustic wave was identified as the proton beam based on the correlation between acoustic emission arrival time and distance between the hydrophone and proton beam. The acoustic frequency spectrum peaked at 10 kHz, and the acoustic pressure amplitude increased monotonically with increasing proton current.
Conclusions:
The authors report the first observation of acoustic emissions generated by a proton beam from a hospital-based clinical cyclotron. When modulated by an electronic function generator, the cyclotron is capable of creating proton spills with fast rise times (18 μs) and high instantaneous currents (790 nA). Measurements of the proton-generated acoustic emissions in a clinical setting may provide a method for in vivo proton range verification and patient monitoring.
More Related Videos
09:05Generation and Quantitative Analysis of Pulsed Low Frequency Ultrasound to Determine the Sonic Sensitivity of Untreated and Treated Neoplastic Cells
Published on: July 22, 2015
06:28Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
Published on: January 30, 2020
Related Concept Videos
Atomic Emission Spectroscopy: Instrumentation
Types of Radioactivity
Alpha (α) decay is the emission of an α particle from the nucleus. For example, polonium-210 undergoes α decay:
Generating Electromagnetic Radiations
Nuclear Transmutation