Related Experiment Video
Updated: Mar 29, 2026

Using the Droplet Transfer Method to Reliably Prepare Giant Unilamellar Vesicles
Published on: September 19, 2025
[Improvement of the Convenience of White Petrolatum]
Kanami Takaya1, Michiteru Ohtani, Akane Nozawa
1Department of Hospital Pharmacy, Tokyo Teishin Hospital.
Abstract:
White petrolatum is frequently used as an oleaginous base, but has a drawback of poor usability. In this trial, white petrolatum was prepared at a lower melting point to improve its usability. Characteristic pharmaceutical values such as melting point, yield, and consistency were compared between a conventional product and ophthalmic white petrolatum. Usability was compared by administering a survey questionnaire and evaluating the comparable moisturizing effect by conductivity in humans. The melting point and yield value of the improved product were significantly lower compared with other white petrolatum products. In the survey, the improved product was rated excellent in five criteria. On a scale of 1 to 5, the average values for the five criteria for the improved product were 4.7, while the conventional product and ophthalmic white petrolatum were rated 3.0 and 3.5, respectively. No difference in moisturizing effect was observed among all petrolatums after application, from day 1 to day 14. In conclusion, the improved white petrolatum demonstrated better usability, and the moisturizing effect was equivalent to conventional product, suggesting that the use of this improved product may lead to improved adherence.
More Related Videos
05:32Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
Published on: September 21, 2015
05:43Preparation of Giant Vesicles Encapsulating Microspheres by Centrifugation of a Water-in-oil Emulsion
Published on: January 24, 2017
Related Concept Videos
Bioavailability Enhancement: Drug Permeability Enhancement
Hand hygiene
Hand washing...
Plasticizers
Plasticizers function by using surface-active agents to create repulsive electrostatic forces between cement particles. This dispersion enhances the concrete's...
Bioavailability Enhancement: Drug Solubility Enhancement
Ophthalmic Drug Delivery Systems
In Vitro Drug Dissolution: Alternative Methods