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Association Between Family History and Hypertension Among Chinese Elderly
1From the Institute of Geriatrics, Chinese PLA General Hospital, Beijing Key Laboratory of Aging and Geriatrics (ML, YH, JW, LW, YW, DZ, JZ, YY), State Key Laboratory of Kidney Disease (YH), and Department of Chinese Traditional Medicine and Acupuncture (BJ), Chinese PLA General Hospital, Beijing, China.
Medicine
|December 4, 2015
Summary
Family history significantly increases hypertension risk in Chinese elderly, with higher blood pressure even in those without hypertension. This graded association was observed in both genders, highlighting genetic predisposition.
Area of Science:
- Gerontology
- Cardiovascular Health
- Epidemiology
Background:
- Hypertension is a major global health concern, particularly in aging populations.
- Family history is a known risk factor for hypertension, but its graded impact requires further investigation.
Purpose of the Study:
- To assess the association between family history and hypertension prevalence in Chinese elderly.
- To explore potential gender differences in this association.
Main Methods:
- A population-based cross-sectional study was conducted in Beijing, China, in 2014.
- Family history was categorized into no history (FH0), one generation (FH1), and two generations (FH2) of first-degree relatives with hypertension.
- Multiple logistic regression analysis was employed to determine the trend.
Main Results:
- The overall prevalence of hypertension was 53.0%.
- Individuals with a positive family history exhibited a significantly higher hypertension prevalence (67.5%) compared to those without (47.9%).
- A significant, graded linear trend of increasing hypertension prevalence and elevated blood pressure levels was observed with increasing family history categories in both genders (P for trend < 0.001).
Conclusions:
- Family history demonstrates a significant and graded association with hypertension and blood pressure levels among Chinese elderly.
- This association is evident even in individuals without diagnosed hypertension, suggesting a genetic predisposition.
- The findings underscore the importance of considering family history in hypertension risk assessment and management strategies for older adults.
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