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Obesity is the strongest predictor of obstructive sleep apnea (OSA) risk in Black adults with metabolic syndrome. This finding highlights the need for targeted interventions to reduce OSA-related cardiovascular disease in this population.

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Area of Science:

  • Cardiology
  • Sleep Medicine
  • Public Health

Background:

  • Obstructive sleep apnea (OSA) is linked to cardiovascular disease (CVD).
  • Identifying OSA risk factors is crucial for effective CVD prevention strategies.
  • The Metabolic Syndrome Outcome Study (MetSO) offers insights into OSA risk in Black adults with metabolic syndrome.

Purpose of the Study:

  • To investigate the risk factors for OSA in Black individuals diagnosed with metabolic syndrome.
  • To determine the strongest predictors of OSA risk within this specific demographic.

Main Methods:

  • Utilized data from 1,035 Black participants in the MetSO cohort.
  • Assessed OSA risk using the Apnea Risk Evaluation System (ARES) questionnaire (score ≥6).
  • Defined obesity by body mass index (BMI ≥ 30 kg/m²).
  • Employed multivariate-adjusted logistic regression to identify predictors.

Main Results:

  • Nearly half (48.9%) of the screened MetSO cohort were at high risk for OSA.
  • Obesity (BMI ≥ 30 kg/m²) was identified as the strongest predictor of OSA risk (OR=1.59).
  • This association remained significant after adjusting for covariates like blood pressure, lipids, and glucose levels.

Conclusions:

  • Black adults in the MetSO cohort exhibit a higher risk for OSA compared to general adult populations in developed countries.
  • Obesity is confirmed as the most significant independent predictor of OSA risk among Black individuals with metabolic syndrome.
  • Findings underscore the importance of managing obesity for OSA and CVD prevention in this population.