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Related Concept Videos

Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

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The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more...
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Drugs Used in Lower Respiratory Disorders: Overview01:17

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Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
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Probiotics01:22

Probiotics

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Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
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Allergic Reactions02:06

Allergic Reactions

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Overview
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Related Experiment Video

Updated: Mar 29, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
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PROBIOTICS AND ALLERGIC RESPIRATORY DISEASES.

M Miraglia Del Giudice1, C Indolfi1, A Allegorico1

  • 1Department of Women, Child and General and Special Surgery, Second University of Naples, Naples, Italy.

Journal of Biological Regulators and Homeostatic Agents
|December 5, 2015
PubMed
Summary
This summary is machine-generated.

Probiotics can help manage allergies by restoring gut health and reducing inflammation. Clinical studies show their effectiveness in treating conditions like atopic dermatitis and allergic respiratory diseases.

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Area of Science:

  • Immunology
  • Microbiology
  • Gastroenterology

Background:

  • Probiotics modulate the gut microbiome and intestinal barrier function.
  • Allergic inflammation involves immune responses and pro-inflammatory cytokines.
  • Gut health is increasingly linked to systemic immune conditions.

Purpose of the Study:

  • To summarize the role of probiotics in managing allergic inflammation.
  • To review clinical evidence for probiotic efficacy in allergic diseases.
  • To explore probiotic therapeutic potential in respiratory allergies.

Main Methods:

  • Literature review of clinical studies and recent research.
  • Analysis of probiotic mechanisms in gut barrier and immune function.
  • Synthesis of data on probiotic use in atopic dermatitis, food allergies, asthma, and rhinitis.

Main Results:

  • Probiotics restore gut microbiome balance and intestinal permeability.
  • They enhance gut barrier immunological function and reduce inflammation.
  • Clinical studies confirm probiotic efficacy in atopic dermatitis, food allergies, and respiratory allergies like asthma and rhinitis.

Conclusions:

  • Probiotics offer a therapeutic strategy for allergic inflammation.
  • Oral probiotics demonstrate efficacy in treating and preventing atopy.
  • Further research supports probiotics for allergic respiratory conditions.