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Updated: Mar 29, 2026

Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
Two Photon Induced Luminescence of BSA Protected Gold Clusters
Sangram L Raut1, Dmytro Shumilov2, Rahul Chib1
1Center for Commercialization of Fluorescence Technologies, University of North Texas Health Science Center, 3500 Camp Bowie Blvd. Fort Worth, Texas, USA, 76107.
Abstract:
In this short letter, we have synthesized the BSA protected Au25 nanoclusters and studied their two photon luminescence behavior. We demonstrate that BSA Au25 nanoclusters can be used as a probe with two photon excitation capability. Our results show a quadratic relation between excitation power and emission intensity whereas with one photon excitation shows a linear dependence. The emission spectrum of BSA Au25 nanoclusters with one photon and two photon excitation shows no appreciable change. Due to its long wavelength emission (650 nm) and two photon excitation, BSA Au25 can be potentially used as a probe for deep tissue imaging.

