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Tourette syndrome. The pediatric perspective.

G S Golden

    American Journal of Diseases of Children (1960)
    |May 1, 1977
    PubMed
    Summary

    Tourette syndrome in children often begins around age 6 with tics and vocalizations. Early diagnosis and haloperidol treatment show significant improvement in most pediatric patients.

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    Area of Science:

    • Neurology
    • Pediatrics
    • Child Psychiatry

    Background:

    • Tourette syndrome is a complex neurological disorder affecting children.
    • Characterized by involuntary motor and vocal tics.
    • Diagnosis can be delayed, impacting management.

    Purpose of the Study:

    • To detail the clinical presentation of Tourette syndrome in a pediatric cohort.
    • To investigate diagnostic delays and treatment outcomes.
    • To explore associated neurological and academic factors.

    Main Methods:

    • Clinical case series of 15 children diagnosed with Tourette syndrome.
    • Retrospective review of medical histories and examination findings.
    • Assessment of treatment response to haloperidol.

    Main Results:

    • Typical onset around age 6 with initial symptoms like eyeblinking.
    • Development of diverse tics and vocalizations, with infrequent coprolalia/echolalia.
    • Average diagnostic delay of four years.
    • Haloperidol treatment yielded good to excellent response in 75% of patients.
    • Associated factors include encephalopathic events, "soft" neurological signs, and school difficulties.
    • Personal and social adjustments were generally positive.

    Conclusions:

    • Tourette syndrome in children presents with specific early symptoms and diagnostic challenges.
    • Haloperidol is an effective treatment option for pediatric Tourette syndrome.
    • Despite associated issues, affected children often achieve good social and personal adjustment.

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