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Impact of Cardiogenic Vomiting in Patients with STEMI: A Study From China
Zongsheng Guo1, Xinchun Yang1, Mulei Chen1
1Department of Cardiology, Beijing Chao-yang Hospital Attached to Capital Medical University, Beijing, China (mainland).
Insights
Cardiogenic vomiting in ST-elevation myocardial infarction (STEMI) patients is a significant predictor of adverse cardiac events. This symptom indicates a higher risk for major adverse cardiac events (MACE) post-hospitalization.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- ST-elevation myocardial infarction (STEMI) presents with varied symptoms.
- Vomiting and syncope are serious STEMI symptoms affecting outcomes.
- The impact of cardiogenic vomiting on STEMI prognosis requires investigation.
Purpose of the Study:
- To determine if cardiogenic vomiting predicts clinical outcomes in STEMI patients.
- To assess the association between vomiting and major adverse cardiac events (MACE) in STEMI.
Main Methods:
- 152 STEMI patients were divided into two groups based on vomiting.
- Demographics, hospitalization conditions, and 6-month MACE were recorded.
- Multivariate Cox regression analysis was used to identify predictors of MACE.
Main Results:
- No significant demographic differences were found between groups.
- Patients with vomiting (Group A) had more severe hospitalization conditions.
- The MACE rate was significantly higher in the vomiting group (67.7%) versus the non-vomiting group (27.8%).
- Cardiogenic vomiting was identified as an independent predictor of MACE.
Conclusions:
- Cardiogenic vomiting is a valuable predictor of MACE in STEMI patients.
- Vomiting indicates increased risk during hospitalization and after discharge.
- Identifying cardiogenic vomiting aids in risk stratification for STEMI patients.
Abstract:
BACKGROUND Different patients with ST-elevation myocardial infarction (STEMI) have different symptoms. A third of them may have medical emergencies caused by symptoms such as vomiting and syncope. These concomitant symptoms may influence subsequent therapy and final outcomes. The aim of this study was to determine whether cardiogenic vomiting is a predictor of clinical outcomes in patients with STEMI. MATERIAL AND METHODS We classified 152 STEMI patients from different areas into 2 groups on the basis of vomiting: group A and group B. Their demographics and conditions of hospitalization were recorded. After follow-up, major adverse cardiac events (MACE) were regarded as study endpoints for the effect of cardiogenic vomiting in STEMI patients. RESULTS We found no significant difference in demographic and clinical characteristics of the 2 groups (P>0.05). The hospitalized conditions of group A were more serious than in group B. During a follow-up of 6 months, MACE rate was higher in vomiting patients (42; 67.7%) compared with group B (25; 27.8%). Multivariate Cox regression analysis revealed that cardiogenic vomiting was an independent predictor of clinical outcomes. CONCLUSIONS Cardiogenic vomiting is a useful predictor of major adverse cardiac events in STEMI patients for the hospitalization and after discharge.
