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Updated: Mar 29, 2026

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
[Mechanisms of the Effects of Probiotics on Symbiotic Digestion]
Abstract:
The published data and our own data on the mechanisms of the influence of microbial probiotics, prebiotics, and their combinations on the processes of symbiotic digestion have been considered and generalized. It is shown that the effects on an organism are associated with the enhanced metabolic activity of intestinal bacteria: stimulation of bacterial fermentation of carbohydrates and formation of short-chained fatty acids, an increase in the blotting capacity of the intestines due to elongation of villi and deepening of crypts, and a decrease in secretion of toxic proteolytic products (ammonia, phenols, thiols, indoles, etc.). It has been shown that a combination of probiotics and prebiotic enhances the biological efficiency of a complex preparation, which contributes to activation of carbohydrate, protein, and mineral metabolism.
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