Related Experiment Video
Updated: Mar 29, 2026

LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring
Published on: November 17, 2018
Statins and atherosclerosis: the role of epigenetics
Marcelo Storino Farina1, Jairo Rojano Rada2, Antony Molina Garrido2
1SServicio de Medicina Interna, Hospital Dr. Miguel Pérez Carreño, IVSS, Caracas, Venezuela. Clínica Fénix Salud, Caracas, Venezuela. Address: Edificio Loma Escondida, Piso 8, Apartamento 87, Urbanización Lomas del Ávila, Palo Verde, Municipio Sucre, Estado Miranda CP 1070, Venezuela.
Abstract:
Atherosclerosis is an immune-inflammatory disease, in which pathophysiological mechanisms include inflammation patterns and epigenetic changes that alter gene expression of several inflammatory and non-inflammatory mediators. Epigenetics is offering explanations on how diet, environmental factors and lifestyle can influence the onset and progression of the disease, and how these alterations can be transmitted to the following generations without any changes in DNA sequences. Statins, through their pleiotropic effects, provide a useful tool in controlling the progression of plaques and their subsequent impact.
Related Concept Videos
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Atherosclerosis III: Management
Cholesterol: Significance and Regulation
Considering cholesterol and...
Atherosclerosis I: Introduction
Pharmacogenomics: Identification of New Drug Targets
Coronary Artery Disease I: Introduction
