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Nutritional deficiency and the skin.

S J Miller1

  • 1Division of Dermatology, University of California, San Diego School of Medicine.

Journal of the American Academy of Dermatology
|July 1, 1989
PubMed
Summary

Nutritional deficiencies and inherited metabolic disorders can cause significant skin changes. Sunscreen use also impacts skin health by inhibiting vitamin D synthesis.

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Area of Science:

  • Dermatology
  • Nutritional Science
  • Medical Genetics

Background:

  • Skin manifestations are common indicators of nutritional deficiencies.
  • Various inherited metabolic disorders also present with distinct cutaneous symptoms.
  • Environmental factors like sunscreen use can affect skin's physiological processes.

Purpose of the Study:

  • To review the association between nutritional status and skin health.
  • To highlight the role of inherited metabolic disorders in dermatological presentation.
  • To discuss factors affecting cutaneous vitamin synthesis.

Main Methods:

  • Literature review of nutritional deficiencies and skin changes.
  • Analysis of inherited metabolic disorders with cutaneous manifestations.
  • Examination of factors influencing vitamin D synthesis in the skin.

Main Results:

  • Deficiencies in ascorbic acid, retinol, protein-energy, cyanocobalamin, phytonadione (vitamin K), biotin, riboflavin, pyridoxine, niacin, essential fatty acids, and zinc are linked to skin changes.
  • Inherited disorders of copper, biotin, zinc, and tryptophan metabolism present with cutaneous symptoms.
  • Sunscreen use inhibits cutaneous vitamin D synthesis.

Conclusions:

  • Cutaneous changes serve as important clinical signs for various nutritional deficiencies and metabolic disorders.
  • Understanding these links aids in diagnosis and management of dermatological conditions.
  • Further research into nutritional pathways and skin health is warranted.

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