The effectiveness of two disinfectants on denture base acrylic resin with an organic load

This study compared the biocidal effectiveness of chlorine dioxide and 5.25% sodium hypochlorite (diluted 1:10) on acrylic resin strips inoculated with Staphylococcus aureus, Candida albicans, or Escherichia coli in the presence of an organic load. Sterile acrylic resin strips were immersed in a solution containing 10% horse serum and 10(5) to 10(7) organisms/ml for each type of organism, then disinfected in chlorine dioxide, sodium hypochlorite, or 0.9 sterile saline for 30 seconds or 1, 2, or 4 minutes. After disinfection, the strips were neutralized and incubated for 72 hours. The results showed a difference between the ability of chlorine dioxide and sodium hypochlorite to kill the test organisms on acrylic resin strips when organic matter is present. Chlorine dioxide achieved complete disinfection of all three organisms within 2 minutes. Sodium hypochlorite achieved complete disinfection of all three organisms within 4 minutes.