Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Equipments Used To Measure Blood Pressure

Equipments Used To Measure Blood Pressure

Direct Method
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Goat and cow-milk based infant formulas contain extracellular vesicles with different miRNA and protein cargo.

Current research in food science·2026

Same author

Financial Toxicity in Cervical Cancer Patients Undergoing Radical Treatment With External Beam Radiation and Brachytherapy at a Tertiary New Zealand Radiation Oncology Centre.

Journal of medical imaging and radiation oncology·2026

Same author

Evaluation of the reproducibility and factors affecting perfusion measurement in normal pregnancies with single-slice FAIR Arterial Spin Labeling (ASL).

Placenta·2026

Same author

Characterization of extracellular vesicles at parturition in dairy cows with late-gestation heat stress.

JDS communications·2026

Same author

Family History and Solar Insolation in Bipolar I Disorder.

Acta psychiatrica Scandinavica·2026

Same author

Chronic meningoencephalitis due to enterovirus A71 complicating rituximab therapy.

Revue neurologique·2025

Search research articles

Related Experiment Video

Updated: Mar 29, 2026

Diffuse Reflectance Spectroscopy: Getting the Capillary Refill Test Under One's Thumb

Diffuse Reflectance Spectroscopy: Getting the Capillary Refill Test Under One's Thumb

Published on: December 2, 2017

An automated quasi-continuous capillary refill timing device.

L L Blaxter¹, D E Morris, J A Crowe

¹Electrical Systems & Optics Research Division, Faculty of Engineering, University of Nottingham, University Park, Nottingham NG7 2RD, UK.

Physiological Measurement

|December 8, 2015

Summary

This study introduces an automated system for measuring capillary refill time (CRT), overcoming manual assessment limitations. The novel device offers standardized, objective cardiovascular assessment for improved clinical integration.

More Related Videos

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Published on: May 10, 2024

Non-invasive Assessment of Microvascular and Endothelial Function

Non-invasive Assessment of Microvascular and Endothelial Function

Published on: January 29, 2013

Related Experiment Videos

Last Updated: Mar 29, 2026

Diffuse Reflectance Spectroscopy: Getting the Capillary Refill Test Under One's Thumb

Diffuse Reflectance Spectroscopy: Getting the Capillary Refill Test Under One's Thumb

Published on: December 2, 2017

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Published on: May 10, 2024

Non-invasive Assessment of Microvascular and Endothelial Function

Non-invasive Assessment of Microvascular and Endothelial Function

Published on: January 29, 2013

Area of Science:

Biomedical Engineering
Cardiovascular Physiology
Medical Device Technology

Background:

Capillary refill time (CRT) is a clinical indicator of cardiovascular function.
Manual CRT assessment is prone to variability due to lighting, pressure, and subjective interpretation.
Standardization is needed to improve the reliability of CRT measurements.

Purpose of the Study:

To develop and evaluate a novel automated system for objective CRT measurement.
To overcome the limitations associated with manual CRT assessment.
To facilitate integration of CRT into electronic health records and monitoring systems.

Main Methods:

A non-invasive adhesive sensor with a pneumatic actuator and multi-wavelength reflectance device was developed.
A battery-operated datalogger unit provided a self-contained pneumatic supply.
PC-based software analyzed sensor data for refill time, skin temperature, and signal quality.

Main Results:

Automated CRT datasets were collected from 30 healthy volunteers (15 adults, 15 children) during controlled cooling.
Analysis of volunteer data demonstrated the system's ability to capture CRT variations.
Detailed analysis of two datasets confirmed that automated CRT responses to cooling align with previous research.

Conclusions:

The automated CRT system offers a standardized and objective method for cardiovascular assessment.
This technology has the potential to reduce clinician workload and enhance patient monitoring.
Further integration into clinical workflows can improve diagnostic accuracy and patient care.