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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

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Heart rate variability improvement in children using transcatheter atrial septal defect closure

İsa Özyılmaz1, Yakup Ergül, Hasan Tahsin Tola

  • 1Department of Pediatric Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center and Research Hospital; İstanbul-Turkey. isaozy@hotmail.com.

Anatolian Journal of Cardiology
|December 8, 2015
PubMed

Insights

Transcatheter closure of atrial septal defects (ASD) positively impacts heart rate variability (HRV) in children. Autonomic function, measured by HRV, recovers to normal levels within six months post-procedure.

Area of Science:

  • Cardiology
  • Pediatric Medicine
  • Autonomic Nervous System Research

Background:

  • Atrial septal defect (ASD) can affect autonomic nervous system function.
  • Heart rate variability (HRV) is a key indicator of autonomic behavior.
  • Transcatheter closure is a common treatment for ASD in pediatric patients.

Purpose of the Study:

  • To evaluate the effect of transcatheter ASD closure on heart rate variability (HRV) in children.
  • To assess changes in time-domain and frequency-domain HRV parameters before and after the procedure.
  • To determine the long-term recovery of HRV following transcatheter ASD closure.

Main Methods:

  • A prospective study involving 47 pediatric patients undergoing transcatheter ASD closure and 30 healthy controls.
  • Holter electrocardiography (ECG) was performed pre-procedure, one day post-procedure, and six months post-procedure.
  • Analysis of time-domain (SDNN, rMSSD, SDANN) and frequency-domain (VLF, LF, HF, VHF, LF/HF) HRV parameters using Student's t-test.

Main Results:

  • Pre-procedure, pediatric ASD patients exhibited lower HRV values compared to healthy controls in both time and frequency domains.
  • Following transcatheter closure, HRV values in the patient group gradually approached those of the control group.
  • By six months post-procedure, HRV parameters in the patient group showed no statistically significant difference compared to the control group.

Conclusions:

  • Transcatheter closure of secundum ASDs has a beneficial effect on pediatric HRV.
  • Improved HRV post-procedure suggests a potential reduction in mortality and morbidity.
  • Pediatric HRV demonstrates recovery approximately six months after transcatheter ASD closure.
Abstract

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