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Lipid Status and Predisposing Genes in Patients with Diabetes Mellitus Type 1 from Various Ethnic Groups
L I Kolesnikova1, S I Kolesnikov1, M A Darenskaya2
1Research Center for Family Health Problems and Human Reproduction, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia.
Abstract:
The peculiarities of HLA class II profile and lipid metabolism were examined in Buryat and Russian ethnic groups of patients with diabetes mellitus type 1. The incidence of type 1 haplotypes in HLA class II gene family was lower in Buryats than that in Russians. In comparison with Russians, the course of diabetes mellitus type 1 in Buryat patients was characterized with a lower content of total lipids, triacylglycerols, total cholesterol, and LDL, which probably explains a more favorable course of the disease in Buryat population.
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