"Are CRT upgrade procedures more complex and associated with more complications than de novo CRT implantations?" A
I A H Ter Horst1, Y Kuijpers2, J van 't Sant3
1Department of Cardiology, University Medical Center Utrecht, Heidelberglaan 100, PO Box 85500, 3508 GA, Utrecht, The Netherlands. i.a.h.terhorst@umcutrecht.nl.
Insights
Cardiac resynchronisation therapy (CRT) upgrades are as safe and straightforward as new CRT device implantations. This study found no significant differences in complexity or complication rates between the two procedures.
Area of Science:
- Cardiology
- Medical Devices
- Electrophysiology
Background:
- Cardiac resynchronisation therapy (CRT) is a vital treatment for heart failure.
- Understanding the safety and complexity of CRT device procedures is crucial for patient care.
- Comparing upgrade procedures to de novo implantations provides insights into procedural risks.
Purpose of the Study:
- To determine if cardiac resynchronisation therapy (CRT) upgrade procedures are more complex than de novo implantations.
- To evaluate whether CRT upgrade procedures are associated with a higher complication rate compared to de novo implantations.
Main Methods:
- A retrospective comparison of 134 CRT upgrade procedures with an equal number of de novo CRT implantations.
- Analysis of procedural data, including duration, radiation, and hospitalization.
- Assessment of periprocedural (≤30 days) and long-term (≤1 year) device-related complications.
Main Results:
- No significant differences were observed in procedure duration, radiation time, or hospitalization between upgrade and de novo groups.
- Perioperative complication rates were similar: 6.7% for upgrades versus 9.0% for de novo implantations.
- Long-term device-related complications with consequences were also comparable: 3.5% for upgrades versus 4.9% for de novo implantations.
Conclusions:
- Cardiac resynchronisation therapy (CRT) upgrade procedures are not more complex than de novo implantations.
- The complication rates for CRT upgrades are similar to those of de novo CRT device implantations.
- These findings support the safety and feasibility of CRT device upgrades.
Objective:
The objective of the study was to examine whether cardiac resynchronisation therapy upgrade procedures are more complex and associated with more complications than de novo implantations.
Method:
We retrospectively compared 134 upgrade procedures performed between 2006-2012 with a random, equally sized, sample of de novo CRT device implantations in the same period. Procedural data and the occurrence of periprocedural (≤ 30 days) and long-term device-related (≤ 1 year) complications were analysed. Complications with consequences were defined as those in need of adjustment of standard care.
Results:
Median time to upgrade was 57 (31-115) months. There were no significant differences in procedure duration, radiation time or total hospitalisation between upgrades and de novo implantations. Perioperative complications occurred in 6.7 % of upgrade patients and in 9.0 % of de novo patients. The most frequently seen complications were phrenic nerve stimulation, coronary sinus dissection and pocket haematoma. Procedure success was comparable (upgrade: 98.5 % versus de novo: 96.3 %). A total of 236 patients completed 1 year of follow-up. Ten (4.2 %) patients had a long-term device-related complication with consequences including phrenic nerve stimulation, lead dislodgement/dysfunction, and infection (upgrade: 3.5 % versus de novo: 4.9 %).
Conclusion:
Upgrade procedures are not more complex nor associated with more complications than de novo CRT implantations.
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