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Updated: Mar 29, 2026

Ole Isacson: Development of New Therapies for Parkinson's Disease
Published on: April 29, 2007
[Evidence-based treatment of psychosis associated with Parkinson's disease]
R Haussmann1, M Bauer2, M Donix2
1Klinik und Poliklinik für Psychiatrie und Psychotherapie, Universitätsklinikum Carl Gustav Carus, Technischen Universität Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland. robert.haussmann@uniklinikum-dresden.de.
Abstract:
Psychotic symptoms in Parkinson's disease are frequent phenomena and are often associated with an immense burden for caregivers, increased risk of nursing home placement and mortality. Treatment of psychotic disorders associated with Parkinson's disease often poses a therapeutic dilemma and necessitates a differentiated risk-benefit assessment as both the reduction of antiparkinsonian drugs and use of antipsychotic drugs can result in deterioration of motor functions. This article gives an overview of relevant clinical aspects and highlights the pharmacological evidence-based treatment options.
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