Stones in 2015: Changes in stone management - suspending belief for evidence

Sapan N Ambani1, Khurshid R Ghani2

  • 1Department of Urology, University of Michigan, 3875 Taubman Center, 1500 E. Medical Center Drive, Ann Arbor, Michigan 48109, USA.

Nature Reviews. Urology
|December 9, 2015
PubMed

Insights

Population studies in 2015 revealed evolving urinary stone management trends. A key randomized trial on medical expulsive therapy significantly impacted current treatment approaches for kidney stones.

Area of Science:

  • Urology
  • Nephrology
  • Evidence-based medicine

Background:

  • Population-based studies in 2015 highlighted shifts in urinary stone management.
  • Identified critical areas needing improvement in contemporary patient care.
  • Meta-analyses represent a high level of evidence in medical research.

Purpose of the Study:

  • To summarize key findings from 2015 regarding urinary stone management.
  • To identify the defining publication in stone management for 2015.
  • To analyze the impact of new evidence on established treatment paradigms.

Main Methods:

  • Review of population-based studies on urinary stones from 2015.
  • Analysis of meta-analyses relevant to stone management.
  • Evaluation of a specific randomized controlled trial on medical expulsive therapy.

Main Results:

  • 2015 studies indicated changing trends in urinary stone treatment.
  • A randomized controlled trial on medical expulsive therapy emerged as a pivotal study.
  • This trial challenged existing understanding and practices in stone management.

Conclusions:

  • The landscape of urinary stone management is dynamic.
  • Randomized controlled trials can significantly alter medical paradigms.
  • Continued research is essential for optimizing patient outcomes in urology.

Related Concept Videos

Quarrying of Stone01:15

Quarrying of Stone

Quarrying is the process of extracting stone from a quarry, where specialized techniques are employed to remove large blocks of stone safely and efficiently. This process can involve controlled explosions or more precision-oriented methods such as cutting and drilling.
One common method involves using a diamond belt saw to cut large blocks from the quarry face. These blocks can be about 50 feet long and 12 feet high. After the initial vertical cut, drilling is performed at the base of the...
732
Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
322
Stone Masonry01:29

Stone Masonry

Stone masonry is a construction technique that uses individual stones to build structures and can be categorized into two main types: rubble and ashlar. Rubble masonry uses uneven, naturally shaped stones such as river rocks or fragments from quarries. This method often requires the mason to select and possibly shape each stone to fit the designated space, ensuring a proper build, even with irregular stone sizes and shapes. Ashlar masonry, on the other hand, employs uniformly cut stones that...
629
Types of Building Stone01:30

Types of Building Stone

Building stones, essential materials for construction, are extracted from natural rock deposits and processed into specific forms and dimensions suitable for various building applications. These stones are broadly classified into three types based on their geological formation: igneous, sedimentary, and metamorphic.
Igneous rocks are formed from the solidification of magma or lava. An example is granite, known for its durability and resistance to weathering, making it ideal for parts of...
577
Urinary Tract Calculi V: Nursing Management01:28

Urinary Tract Calculi V: Nursing Management

AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
419
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
635