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Aneuploidy as a prognostic factor in breast cancer
1Department of Surgery, Södersjukhuset, Stockholm, Sweden.
Abstract:
The predictive value of nuclear DNA content in mammary carcinoma is still under debate in spite of several reports indicating a relationship between DNA ploidy and prognosis. The impact of differences in methodology on the evaluation of DNA data is discussed, and a recent study demonstrating DNA ploidy as a statistically significant prognostic variable on a prospective material of breast cancer patients is presented.