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Is androgen substitution necessary in hypogonadal patients when they are treated with chemotherapy for malignant
N Pavlidis1, N Nikolaou, C Tolis
1Department of Medicine, Hippocration General Hospital, Athens, Greece.
Medical and Pediatric Oncology
|January 1, 1989
Abstract:
A patient with hypogonadotropic hypogonadism owing to endogenous gonadotropin releasing hormone deficiency, who developed Hodgkin's disease is described. Chemotherapy administration caused prolonged and life-threatening myelosuppression; androgen substitution seemed to reverse bone marrow function and to maintain normal peripheral blood counts. Whether or not androgens are a necessary substitution in hypogonadal patients suffering from cancer and undergoing chemotherapy is discussed.