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ALCOdb: Gene Coexpression Database for Microalgae.

Yuichi Aoki1, Yasunobu Okamura2, Hiroyuki Ohta3

  • 1Graduate School of Information Sciences, Tohoku University, 6-3-09, Aramaki-Aza-Aoba, Aoba-ku, Sendai, 980-8579 Japan Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan.

Plant & Cell Physiology
|December 9, 2015
PubMed
Summary
This summary is machine-generated.

The Algae Gene Coexpression database (ALCOdb) aids research into microalgal genes for biofuels and food. It helps identify gene functions and biological roles, advancing microalgal studies.

Keywords:
Chlamydomonas reinhardtiiComparative transcriptomicsCyanidioschyzon merolaeDatabaseGene coexpressionMicroalgae

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Area of Science:

  • * Microalgal biotechnology
  • * Functional genomics
  • * Bioinformatics

Background:

  • * Microalgae are vital for biofuels and food due to energy and food shortages.
  • * Limited functional characterization of microalgal genes hinders research.
  • * Understanding gene function is crucial for optimizing microalgal applications.

Purpose of the Study:

  • * To develop a comprehensive database for microalgal gene coexpression analysis.
  • * To provide tools for exploring gene modules and functions in model algae.
  • * To facilitate the functional annotation of uncharacterized microalgal genes.

Main Methods:

  • * Development of the Algae Gene Coexpression database (ALCOdb).
  • * Inclusion of data for *Chlamydomonas reinhardtii* and *Cyanidioschyzon merolae*.
  • * Implementation of data retrieval through Coexpressed Gene List, Gene Information, and Coexpressed Gene Network pages.

Main Results:

  • * ALCOdb provides gene coexpression information for two model microalgae.
  • * Advanced tools include an expression profile viewer and a differentially expressed gene search.
  • * Demonstrated utility in detecting functionally related genes and inferring biological roles.

Conclusions:

  • * ALCOdb is a valuable resource for microalgal research.
  • * The database facilitates studies on lipid metabolism and organelle development.
  • * Promotes evolutionary understanding of plant cellular systems and microalgal biotechnology.