Related Experiment Video
Updated: Mar 29, 2026

04:18
Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
661
Maternal periodontal disease and preterm birth: A case-control study
Pushpalatha Govindaraju1, Sanjay Venugopal1, Madhura Antharasanahalli Shivakumar1
1Department of Periodontics, Sree Siddhartha Dental College and Research Center, Agalakote, Tumkur, Karnataka, India.
Journal of Indian Society of Periodontology
|December 9, 2015
Summary
Maternal periodontitis is linked to preterm birth (PTB). This study found poorer periodontal health in mothers with PTB, suggesting a connection between gum disease and premature delivery.
Area of Science:
- Obstetrics and Gynecology
- Periodontology
- Public Health
Background:
- Preterm birth (PTB) is a leading cause of infant mortality.
- Systemic diseases may influence PTB, with recent focus on maternal periodontitis.
- Investigating the link between periodontitis and PTB is crucial for public health.
Purpose of the Study:
- To examine the relationship between maternal periodontitis and preterm birth.
- To determine if periodontal status is associated with adverse pregnancy outcomes.
Main Methods:
- Recruited 40 healthy primiparous mothers (18-35 years).
- Categorized participants into PTB (n=20) and full-term birth (FTB, n=20) groups.
- Collected data on periodontal status, pregnancy outcomes, and other influencing factors within 2 days of labor.
Main Results:
- PTB group showed significantly shorter gestational periods and lower infant birth weights.
- Mothers in the PTB group exhibited statistically poorer periodontal status compared to the FTB group.
- A positive correlation was observed between gestational age and clinical periodontal parameters.
Conclusions:
- An association exists between periodontitis and gestational age.
- A positive correlation was found between PTB and periodontitis.
- Further research is needed to confirm periodontal disease as an independent risk factor for PTB.
Related Concept Videos
Development of the Oral Microbiota
25
The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
25
Development of Human Microbiota
21
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
21
Pathophysiology of Diabetes
4.3K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
4.3K

