Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

115
Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...
115

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Triptolide protects rat heart against pressure overload-induced cardiac fibrosis.

International journal of cardiology·2013
Same author

Multiresidue pesticide analysis of botanical dietary supplements using salt-out acetonitrile extraction, solid-phase extraction cleanup column, and gas chromatography-triple quadrupole mass spectrometry.

Analytical chemistry·2013
Same author

Interaction domains of p62: a bridge between p62 and selective autophagy.

DNA and cell biology·2013
Same author

Predictors of seizure freedom after surgical management of tuberous sclerosis complex: a systematic review and meta-analysis.

Epilepsy research·2013
Same author

Temporary ileostomy versus colostomy for colorectal anastomosis: evidence from 12 studies.

Scandinavian journal of gastroenterology·2013
Same author

Localized leptin release may be an important mechanism of curcumin action after acute ischemic injuries.

The journal of trauma and acute care surgery·2013

Related Experiment Video

Updated: Mar 29, 2026

Highly Stable, Functional Hairy Nanoparticles and Biopolymers from Wood Fibers: Towards Sustainable Nanotechnology
11:32

Highly Stable, Functional Hairy Nanoparticles and Biopolymers from Wood Fibers: Towards Sustainable Nanotechnology

Published on: July 20, 2016

12.7K

Stimuli-responsive nanoparticles from ionic cellulose derivatives.

Yonggui Wang1, Thomas Heinze2, Kai Zhang1

  • 1Wood Technology and Wood Chemistry, Georg-August-Universität Göttingen, Büsgenweg 4, D-37077 Göttingen, Germany. kzhang1@uni-goettingen.de.

Nanoscale
|December 10, 2015
PubMed
Summary
This summary is machine-generated.

Researchers developed novel stimuli-responsive nanoparticles from sustainable cellulose derivatives. Ionic cellulose derivatives with tertiary amines showed pH-responsive, switchable sizes, offering a new approach for advanced nanomaterials.

More Related Videos

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
06:26

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

2.0K
3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds
06:36

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds

Published on: April 24, 2019

10.3K

Related Experiment Videos

Last Updated: Mar 29, 2026

Highly Stable, Functional Hairy Nanoparticles and Biopolymers from Wood Fibers: Towards Sustainable Nanotechnology
11:32

Highly Stable, Functional Hairy Nanoparticles and Biopolymers from Wood Fibers: Towards Sustainable Nanotechnology

Published on: July 20, 2016

12.7K
Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
06:26

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

2.0K
3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds
06:36

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds

Published on: April 24, 2019

10.3K

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Nanotechnology

Background:

  • Stimuli-responsive nanoparticles (NPs) are crucial for advanced applications.
  • Exploration of NPs from sustainable polymeric feedstock lags behind synthetic polymers.
  • Cellulose-based NPs offer a sustainable alternative but require further development.

Purpose of the Study:

  • To synthesize novel ionic cellulose derivatives for stimuli-responsive NPs.
  • To investigate the influence of terminal functional groups on NP properties.
  • To establish a facile method for preparing cellulose-derived stimuli-responsive NPs.

Main Methods:

  • Synthesis of cellulose 10-undecenoyl ester (CUE) via esterification.
  • Modification of CUE using photo-induced thiol-ene reactions to create ionic derivatives.
  • Preparation of NPs using nanoprecipitation and characterized by size and stimuli-responsiveness.

Main Results:

  • Ionic cellulose derivatives (CUE-DEAET, CUE-DMAET) with tertiary amines were successfully synthesized.
  • Stable NPs with switchable sizes and pH-responsive behavior were obtained using nanoprecipitation.
  • Altering terminal functional groups proved effective in tuning NP properties.

Conclusions:

  • Novel stimuli-responsive NPs can be prepared from ionic cellulose derivatives.
  • Tertiary amine functional groups are key for achieving pH-responsive and switchable NP sizes.
  • This work presents a new strategy for developing sustainable, functional nanomaterials from cellulose.