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Updated: Mar 29, 2026

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Published on: May 26, 2019
Templated C-C and C-N Bond Formation Facilitated by a Molybdenum(VI) Metal Center
Niklas Zwettler1, Antoine Dupé1, Jörg A Schachner1
1Institute of Chemistry, Inorganic Chemistry, University of Graz , Schubertstrasse 1, 8010 Graz, Austria.
Abstract:
Preparation of molybdenum dioxido complexes with novel iminophenolate ligands bearing pendant secondary amide functionalities led to unprecedented C-C and C-N coupling reactions of two α-iminoamides upon coordination. The diastereoselective cyclization to asymmetric imidazolidines occurs at the metal center in two consecutive steps via a monocoupled intermediate. A meaningful mechanism is proposed on the basis of full characterization of intermediate and final molybdenum-containing products by spectroscopic means and by single-crystal X-ray diffraction analyses. This process constitutes the first example of a diastereoselective self-cyclization of two α-iminoamides.
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