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Outcomes of fundoplication for paediatric gastroesophageal reflux disease
E Pascoe1, T Falvey2, A Jiwane3,4
1Sydney Children's Hospital Randwick (SCH), Sydney, Australia. Emily.pascoe@health.nsw.gov.au.
Insights
Fundoplication surgery for severe gastroesophageal reflux disease (GERD) in children shows mixed results. Many children require anti-reflux medication (ARM) again within six months post-surgery.
Area of Science:
- Pediatric Surgery
- Gastroenterology
Background:
- Gastroesophageal reflux disease (GERD) is a common condition in children.
- Fundoplication is a surgical procedure to treat severe GERD when medical management fails.
Purpose of the Study:
- To evaluate the outcomes of fundoplication surgery in children.
- To identify factors associated with poor outcomes after fundoplication.
Main Methods:
- Retrospective chart review of 119 children who underwent fundoplication between 2006 and 2013.
- Outcomes assessed included need for redo fundoplication and recommencement of anti-reflux medication (ARM) at 6-month follow-up.
Main Results:
- 17.6% of children required redo fundoplication, and 53.8% were recommenced on ARM at 6 months.
- Post-operative complications occurred in 42.2% of patients.
- Concurrent gastrostomy was associated with a higher risk of needing ARM post-surgery.
Conclusions:
- Fundoplication can be effective for severe pediatric GERD.
- However, a significant proportion of children require ongoing medical management post-surgery.
Purpose:
Outcomes of fundoplication in children.
Methods:
In this monocentric retrospective study, chart review was performed on children who underwent fundoplication between 2006 and 2013. Outcomes were defined as the need for redo fundoplication and recommencement of anti-reflux medication (ARM) at 6-month follow-up.
Results:
119 patients underwent fundoplication with a mean age of 4.76 years and 55.5% of these were male. At 6-month follow-up, 21 (17.6%) required redo fundoplication and 64 (53.8%) were recommenced on ARM. Post-operative complications occurred in 50 (42.2%) of children; 30% of those with complications had surgery at less than 1 year of age, and 36% had an associated comorbid condition. Neither being under the age of one nor associated comorbidity was significantly associated with a poor outcome. Concurrent gastrostomy was associated with a higher risk of being back on ARM at 6-month follow-up (p = 0.003). Neither gastrointestinal or respiratory symptoms pre-surgery nor abnormal pre-operative investigations including pH monitoring and endoscopy were predictive of poor outcome post-fundoplication.
Conclusion:
Although fundoplication has a role in the treatment of severe GORD in children, the majority of children in this study needed to restart their anti-reflux medications within 6 months of surgery.
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