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Conjunctival Sensation in Scleritis.

Thanapong Somkijrungroj1,2, Weeraya Pimolrat1, John A Gonzales1,3

  • 1a Francis I. Proctor Foundation , University of California , San Francisco , USA.

Ocular Immunology and Inflammation
|December 10, 2015
PubMed
Summary
This summary is machine-generated.

Conjunctival sensation is reduced in patients with scleritis, particularly in areas of prior inflammation. Herpetic scleritis cases showed decreased sensation even in unaffected areas.

Keywords:
Cochet-Bonnet aesthesiometerconjunctival sensationcorneal sensationscleritis

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Area of Science:

  • Ophthalmology
  • Neuroscience

Background:

  • Scleritis is a serious inflammatory condition affecting the sclera.
  • Understanding the sensory changes in scleritis is crucial for patient management.

Purpose of the Study:

  • To investigate alterations in conjunctival sensation in patients diagnosed with scleritis.
  • To compare sensory perception in inflamed or previously inflamed areas with contralateral healthy tissue.

Main Methods:

  • A retrospective cross-sectional study design was employed.
  • Conjunctival sensation was quantitatively assessed using a Cochet-Bonnet aesthesiometer.
  • Measurements were taken in four quadrants of the bulbar conjunctiva and at sites of active or past inflammation, comparing with the unaffected eye.

Main Results:

  • The study included 28 patients with scleritis (9 active, 19 inactive).
  • Areas of inactive scleritis demonstrated significantly reduced sensation compared to normal contralateral eyes (p<0.001).
  • Patients with herpetic scleritis exhibited significantly lower conjunctival sensation in the affected eye (p<0.001).

Conclusions:

  • Conjunctival sensation is demonstrably decreased in scleritis patients, especially in regions with prior inflammation.
  • Herpetic scleritis is associated with reduced conjunctival sensation, extending to areas without evident prior inflammation.