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Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
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Managing obsessive compulsive disorder.

Vlasios Brakoulias1

  • 1Psychiatry, Sydney Medical School, University of Sydney.

Australian Prescriber
|December 10, 2015
PubMed
Summary

Obsessive compulsive disorder (OCD) requires treatment, with psychological interventions and selective serotonin reuptake inhibitors (SSRIs) as first-line options. Effective SSRI treatment for OCD involves higher doses and a minimum of 12 months to prevent relapse.

Keywords:
antidepressantsanxiety disorderscognitive behavioural therapyobsessive compulsive disorder

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Pharmacology

Background:

  • Obsessive compulsive disorder (OCD) is a distressing mental health condition causing significant disability.
  • Unlike personality traits, OCD necessitates professional intervention.

Purpose of the Study:

  • To outline effective treatment strategies for obsessive compulsive disorder.
  • To provide guidance on the use of psychological interventions and selective serotonin reuptake inhibitors (SSRIs) for OCD management.

Main Methods:

  • Review of current therapeutic guidelines for OCD.
  • Analysis of treatment response patterns to SSRIs in OCD patients compared to depression.
  • Recommendations for SSRI dosing, titration, and treatment duration.

Main Results:

  • Psychological interventions and SSRIs are primary treatments for OCD.
  • OCD patients exhibit a slower response to SSRIs than depression patients.
  • Optimal SSRI dosing involves higher therapeutic ranges, with dose adjustments every two weeks.

Conclusions:

  • Treatment improvements typically stabilize at 12 weeks, necessitating continuation for at least 12 months.
  • Discontinuation of successful treatment carries a substantial risk of relapse.
  • Consistent, long-term treatment is crucial for sustained remission in OCD.